For the Super NES enhancement chip see List of Super NES enhancement chips
![]() | |
Names | |
---|---|
Preferred IUPAC name N-[(2-Bromophenyl)methyl]-2-chloro-N-ethylethan-1-amine | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
| |
| |
Properties | |
C11H15BrClN | |
Molar mass | 276.60 g/mol |
Density | 1.339 g/cm3 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
DSP-4, or N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine, is a neurotoxin selective for noradrenergic neurons, capable of crossing the blood–brain barrier.[1]
It exerts transient effects in peripheral sympathetic neurons, but more permanent changes within neurons of the central nervous system. It can induce long-term depletion in cortical and spinal levels of noradrenaline.[2]
See also
editReferences
edit- ^ Daw NW, Videen TO, Parkinson D, Rader RK (1985). "DSP-4 (N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine) Depletes Noradrenaline in Kitten Visual Cortex Without Altering the Effects of Monocular Deprivation". J. Neurosci. 5 (7): 1925–1933. doi:10.1523/jneurosci.05-07-01925.1985. PMC 6565098. PMID 3926960.
- ^ Jaim-Etcheverry G, Mari'a Zieher L (1980). "DSP-4: A novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats". Brain Res. 188 (2): 513–523. doi:10.1016/0006-8993(80)90049-9. PMID 7370771. S2CID 36955590.
🔥 Top keywords: Akademia e Shkencave e RPS te ShqiperiseAlexandria Ocasio-CortezBilderberg GroupCristiano RonaldoDong XiaowanMinecraftOperation GladioPrimal cutRiot FestStrictly Come Dancing (series 7)Main PageSpecial:SearchWikipedia:Featured picturesKalki 2898 ADUEFA Euro 2024Project 2025.xxxKarel deLeeuw2024 Copa AméricaA Quiet Place: Day OneCleopatraDeaths in 2024Jack Draper (tennis)House of the DragonNikki HiltzDiogo CostaJuiceroOpinion polling for the 2024 United Kingdom general electionUEFA European ChampionshipTheodore StreleskiCristiano RonaldoYouTubeKlay ThompsonCopa AméricaThe Bear (TV series)Elias YmerJoe Biden2024 French legislative electionMerih DemiralMoney in the Bank (2024)Zac EfronBad Boys: Ride or DieInside Out 2Gladiator IIArda GülerKevin OrtegaMemphis DepayMarko ArnautovićCody Gakpo